مقالات علمية
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Thrombotic thrombocytopenic purpura
Thrombotic thrombocytopenic purpura TTP Facts: Platelet microthrombi block off small blood vessels Leads to end organ ischemia and dysfunction RBCs…
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PBMC Isolation using The Miltenyi Biotec MACS Cell Separation Technology
PBMC Isolation using The Miltenyi Biotec MACS Cell Separation Technology The Miltenyi Biotec MACS Cell Separation Technology is one of…
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Distinct Gene Mutations Are Associated With Clinicopathologic Features in Urachal Carcinoma: An Analysis of 30 Cases by Next-Generation Sequencing
Abstract Objectives To investigate the gene mutational profile of urachal carcinoma in correlation with its clinicopathologic features. Methods We analyzed…
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Schistocytes
Schistocytes Helmet cells Facts: Fragmented RBCs Diagnosis: Decreased serum haptoglobin Increased LDH and bilirubin Associated With: Microangiopathic hemolytic anemias (…
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Hematology Lessons Best Lab: Buffy Coat/Layer (Peripheral Blood Mononuclear Cell
Peripheral Blood Mononuclear Cell (PBMC) A peripheral blood mononucleated cell (PBMC) is any WBC having a single round nucleus. Typically lymphocytes, monocytes…
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Too Sensitive or Just Right? A Comparison of Two ALK Antibodies (D5F3 and ALK1) for Assessment of Anaplastic Large Cell Lymphoma
Abstract Objectives To compare the performance of the rabbit monoclonal antihuman CD246 antibody (D5F3 clone) with the established ALK1 clone…
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Red blood cell disorders
Red blood cell disorders Facts: 1.) Anemia 2.) Thalassemias 3.) Polycythemias 4.) Transfusion reactions 5.) Porphyria
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Hematology Lessons Best Lab: Polycythemia
Polycythemia Background Information Polycythemia is a medical condition in which the proportion of blood volume that is occupied by…
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Tumor-Infiltrating Lymphocytes Improve Magee Equation–Based Prediction of Pathologic Complete Response in HR-Positive/HER2-Negative Breast Cancer
Abstract Objectives Magee equation 3 (ME3) is predictive of the pathologic complete response (pCR) to neoadjuvant chemotherapy (NAC) in patients…
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Paroxysmal nocturnal hemoglobinuria
Paroxysmal nocturnal hemoglobinuria PNH Facts: Acquired disorder of hematopoietic cells Complement mediated hemolysis History / PE: Pancytopenia with hemolytic anemia…
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