Hematology Lessons Best Lab: Buffy Coat/Layer (Peripheral Blood Mononuclear Cell

Peripheral Blood Mononuclear Cell (PBMC)

A peripheral blood mononucleated cell (PBMC) is any WBC having a single round nucleus. ^{Typically lymphocytes, monocytes and macrophages are grouped under this classification. These WBCs are a critical component in the immune system to tackle against infection and adapt to pathogenic intruders. The lymphocyte population consists of T cells (CD4 and CD8 positive ~75%), B cells and NK cells (~25% combined).}