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Hematology

Idiopathic thrombocytopenic purpura

Idiopathic thrombocytopenic purpura ITP

  • Facts:
    MC immunologic disorder in women of childbearing age

    Common acquired bleeding disorder of childhood (post viral)

    IgG antibodies against platelets
  • History / PE:
    Easy bruisabilty

    Petechiae

    Occasional epistaxis
  • Diagnosis:
    Diagnosis of exclusion

    Thrombocytopenia

    Normal PT, pTT, Hb, WBC

    Positive CCOMBS’ test
  • Treatment:
    Patients with symptomatic bleeding ( Corticosteroids

    IVIG

    Splenectomy

    Rituximab
  • Notes:
    Platelet transfusions do NOT work
  • See Also:
    Thrombotic thrombocytopenia purpura

    Hemolytic uremic syndrome

    Clotting disorders
  • Associated With:
    Hepatitis C

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