Hematology
Langerhans histiocytosis
Langerhans histiocytosis LCH
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- History / PE:
- Solitary, painful, lytic long bone lesion
Hypercalcemia
Overlying, tender swelling
Pathological fractures
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- Diagnosis:
- Birbeck granules on EM
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- Treatment:
- Typically resolves spontaneously
Treated conservatively -
- Associated With:
- Hand–Schüller–Christian disease (children)